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Search Results for " anti-tumor activity "

20

Compounds

Cat No. Product Name Synonyms Targets
T9135 Epirosmanol Others
Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).
T0855 (R)-Naproxen COX
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis...
T5S0106 Peimisine Ebeiensine RAAS , AChR
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...
T21408 DM1-SMe DM1-SSMe Microtubule Associated
DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell ...
TQ0059 Ilorasertib ABT-348 VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...
T12477 Uzansertib phosphate INCB053914 phosphate Pim
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).
T6426 Buclizine dihydrochloride Longifene,Buclina,Buclizine HCl,UCB-4445 5-HT Receptor , AChR , Histamine Receptor
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ...
T6018 Zosuquidar trihydrochloride Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride P-gp
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3.
T12692 RAS GTPase inhibitor 1 Others
RAS GTPase inhibitor 1 is a inhibitor of RAS GTPase, with anti-tumor activity.
T10342 Antitumor agent-2 Others
Antitumor agent-2 has anti-inflammatory and anti-tumor activity and can be used to study cancer.
T26623 AMRI-59 AMRI 59 Others
AMRI-59 is a potent inhibitor of PrxI with anti-tumor activity.
T23480 U-83836E Others
U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.
TN2356 Tetradehydropodophyllotoxin Dehydropodophyllotoxin Others , Antifungal
Tetradehydropodophyllotoxin (Dehydropodophyllotoxin) has anti-tumor activity.
T20864 7-Troc-paclitaxel Others
7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity.
T3170 Troglitazone CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay Apoptosis , Ferroptosis , PPAR , Autophagy
Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.
T12140 N-Acetyl-Calicheamicin N-Acetyl-Calicheamicin γ,N-Acetyl-γ-calicheamicin Antibacterial
N-Acetyl-Calicheamicin (N-Acetyl-γ-calicheamicin) is an antibiotic with high anti-tumor activity.
TN1531 Cratoxylone Antifungal
Cratoxylone is derived from the bark of the Cochin tree and has anti-plasmodial activity and potential anti-tumor and antioxidant activity.
T19783 Dehydroabiethylamine NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine P450 , PDK
Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.
T8271 10Z-Nonadecenoic acid Endogenous Metabolite
10Z-Nonadecenoic acid is a long-chain fatty acid with anti-tumor activity.
T9582 CLEFMA NF-κB
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects.

Compounds

Epirosmanol
T9135
Synonym:
Target: Others
(R)-Naproxen
T0855
Synonym:
Target: COX
Peimisine
T5S0106
Synonym: Ebeiensine
Target: RAAS, AChR
DM1-SMe
T21408
Synonym: DM1-SSMe
Target: Microtubule Associated
Ilorasertib
TQ0059
Synonym: ABT-348
Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase
Uzansertib phosphate
T12477
Synonym: INCB053914 phosphate
Target: Pim
Buclizine dihydrochloride
T6426
Synonym: Longifene,Buclina,Buclizine HCl,UCB-4445
Target: 5-HT Receptor, AChR, Histamine Receptor
Zosuquidar trihydrochloride
T6018
Synonym: Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride
Target: P-gp
RAS GTPase inhibitor 1
T12692
Synonym:
Target: Others
Antitumor agent-2
T10342
Synonym:
Target: Others
AMRI-59
T26623
Synonym: AMRI 59
Target: Others
U-83836E
T23480
Synonym:
Target: Others
Tetradehydropodophyllotoxin
TN2356
Synonym: Dehydropodophyllotoxin
Target: Others, Antifungal
7-Troc-paclitaxel
T20864
Synonym:
Target: Others
Troglitazone
T3170
Synonym: CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay
Target: Apoptosis, Ferroptosis, PPAR, Autophagy
N-Acetyl-Calicheamicin
T12140
Synonym: N-Acetyl-Calicheamicin γ,N-Acetyl-γ-calicheamicin
Target: Antibacterial
Cratoxylone
TN1531
Synonym:
Target: Antifungal
Dehydroabiethylamine
T19783
Synonym: NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine
Target: P450, PDK
10Z-Nonadecenoic acid
T8271
Synonym:
Target: Endogenous Metabolite
CLEFMA
T9582
Synonym:
Target: NF-κB
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TargetMol