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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9135 | Epirosmanol | Others | |
Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa). | |||
T0855 | (R)-Naproxen | COX | |
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T21408 | DM1-SMe | DM1-SSMe | Microtubule Associated |
DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell ... | |||
TQ0059 | Ilorasertib | ABT-348 | VEGFR , FLT , c-RET , PDGFR , Aurora Kinase |
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ... | |||
T12477 | Uzansertib phosphate | INCB053914 phosphate | Pim |
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively). | |||
T6426 | Buclizine dihydrochloride | Longifene,Buclina,Buclizine HCl,UCB-4445 | 5-HT Receptor , AChR , Histamine Receptor |
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ... | |||
T6018 | Zosuquidar trihydrochloride | Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride | P-gp |
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3. | |||
T12692 | RAS GTPase inhibitor 1 | Others | |
RAS GTPase inhibitor 1 is a inhibitor of RAS GTPase, with anti-tumor activity. | |||
T10342 | Antitumor agent-2 | Others | |
Antitumor agent-2 has anti-inflammatory and anti-tumor activity and can be used to study cancer. | |||
T26623 | AMRI-59 | AMRI 59 | Others |
AMRI-59 is a potent inhibitor of PrxI with anti-tumor activity. | |||
T23480 | U-83836E | Others | |
U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock. | |||
TN2356 | Tetradehydropodophyllotoxin | Dehydropodophyllotoxin | Others , Antifungal |
Tetradehydropodophyllotoxin (Dehydropodophyllotoxin) has anti-tumor activity. | |||
T20864 | 7-Troc-paclitaxel | Others | |
7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity. | |||
T3170 | Troglitazone | CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay | Apoptosis , Ferroptosis , PPAR , Autophagy |
Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity. | |||
T12140 | N-Acetyl-Calicheamicin | N-Acetyl-Calicheamicin γ,N-Acetyl-γ-calicheamicin | Antibacterial |
N-Acetyl-Calicheamicin (N-Acetyl-γ-calicheamicin) is an antibiotic with high anti-tumor activity. | |||
TN1531 | Cratoxylone | Antifungal | |
Cratoxylone is derived from the bark of the Cochin tree and has anti-plasmodial activity and potential anti-tumor and antioxidant activity. | |||
T19783 | Dehydroabiethylamine | NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine | P450 , PDK |
Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity. | |||
T8271 | 10Z-Nonadecenoic acid | Endogenous Metabolite | |
10Z-Nonadecenoic acid is a long-chain fatty acid with anti-tumor activity. | |||
T9582 | CLEFMA | NF-κB | |
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects. |